Balancing force field protein-lipid interactions to capture transmembrane helix-helix association

Atomistic simulations have recently been shown to be sufficiently accurate to reversibly fold globular proteins and have provided insights into folding mechanisms. Gaining similar understanding from simulations of membrane protein folding and association would be of great medical interest. All-atom...

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Bibliographic Details
Main Authors: Domański, J, Sansom, MSP, Stansfeld, P, Best, R
Format: Journal article
Published: American Chemical Society 2018