Analysis of B-cell immune tolerance induction using transgenic mice.

Over the past 15 yr, the use of transgenic mice has led to significant advances in our understanding of immunological tolerance. In a normal repertoire the number of B cells with a single antigen receptor specificity is very small, making the study of their fate difficult. In contrast, animals that...

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Autori principali: Ferry, H, Cornall, R
Natura: Journal article
Lingua:English
Pubblicazione: 2004