Genetic epidemiology of dengue virus in phase III trials of the CYD tetravalent vaccine and implications for efficacy

This study defined the genetic epidemiology of dengue viruses (DENV) in two pivotal phase III trials of the tetravalent dengue vaccine, CYDTDV, and thereby enabled virus genotype-specific estimates of vaccine efficacy (VE). Envelope gene sequences (n=661) from 11 DENV genotypes in 10 endemic countri...

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Bibliographic Details
Main Authors: Rabaa, MA, Girerd-Chambaz, Y, Kien, DTH, Trung, VT, Wills, BA, Bonaparte, M, van der Vliet, D, Langevin, E, Cortes, M, Zambrano, B, Dunod, C, Wartel-Tram, A, Jackson, N, Simmons, CP
Format: Journal article
Published: eLife Sciences 2017