Tryptophan depletion in normal volunteers produces selective impairments in learning and memory.
The amino-acid L-tryptophan is essential in the synthesis of brain serotonin, and its depletion can lead to a widespread reduction in central serotonergic activity. A placebo-controlled cross-over within-subjects design (n = 12) examined the effects of tryptophan depletion on human cognitive perform...
Main Authors: | , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1994
|