Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation
Axially chiral biaryls, as exemplified by 1,1’-bi-2-naphthol (BINOL), are key components of catalysts, natural products and medicines. These materials are synthesized conventionally in enantioenriched form through metal- mediated cross coupling, de novo construction of an aromatic ring, point-to-axi...
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| Format: | Journal article |
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Nature Publishing Group
2017
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