Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.

BACKGROUND: The relative immunogenicity of human immunodeficiency virus type 1 (HIV-1) proteins for CD8+ and CD4+ cell responses has not been defined. METHODS: HIV-1-specific T cell responses were evaluated in 65 chronically HIV-1-infected untreated subjects by interferon- gamma flow cytometry with...

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Bibliographic Details
Main Authors: Ramduth, D, Chetty, P, Mngquandaniso, N, Nene, N, Harlow, J, Honeyborne, I, Ntumba, N, Gappoo, S, Henry, C, Jeena, P, Addo, M, Altfeld, M, Brander, C, Day, C, Coovadia, H, Kiepiela, P, Goulder, P, Walker, B
Format: Conference item
Published: 2005