Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.

Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses.

BACKGROUND: The relative immunogenicity of human immunodeficiency virus type 1 (HIV-1) proteins for CD8+ and CD4+ cell responses has not been defined. METHODS: HIV-1-specific T cell responses were evaluated in 65 chronically HIV-1-infected untreated subjects by interferon- gamma flow cytometry with...

書目詳細資料
Main Authors:	Ramduth, D, Chetty, P, Mngquandaniso, N, Nene, N, Harlow, J, Honeyborne, I, Ntumba, N, Gappoo, S, Henry, C, Jeena, P, Addo, M, Altfeld, M, Brander, C, Day, C, Coovadia, H, Kiepiela, P, Goulder, P, Walker, B
格式:	Conference item
出版:	2005

相似書籍

Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
由: Ramduth, D, et al.
出版: (2009)

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.
由: Draenert, R, et al.
出版: (2003)

Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants.
由: Ramduth, D, et al.
出版: (2008)

Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.
由: Honeyborne, I, et al.
出版: (2006)

Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infants.
由: Thobakgale, C, et al.
出版: (2007)

Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection.
由: Day, C, et al.
出版: (2007)

CD8 T-cell-mediated control of the C clade HIV epidemic in subSaharan Africa
由: Goulder, P
出版: (2007)

Impact of intrapeptide epitope location on CD8 T cell recognition: implications for design of overlapping peptide panels.
由: Draenert, R, et al.
出版: (2004)

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.
由: Draenert, R, et al.
出版: (2004)

The STEP study provides a hint that vaccine induction of the right CD8+ T cell responses can facilitate immune control of HIV.
由: Altfeld, M, et al.
出版: (2011)

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.
由: Honeyborne, I, et al.
出版: (2007)

Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection.
由: Mureithi, M, et al.
出版: (2011)

Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure.
由: Ngumbela, K, et al.
出版: (2008)

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
由: Kiepiela, P, et al.
出版: (2007)

HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.
由: Wherry, E, et al.
出版: (2006)

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus.
由: Altfeld, M, et al.
出版: (2002)

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
由: Kiepiela, P, et al.
出版: (2004)

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected thais
由: Buranapraditkun, S, et al.
出版: (2011)

A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
由: Buranapraditkun, S, et al.
出版: (2011)

Erratum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus (Nature (2002) 420 (434-439))
由: Altfeld, M, et al.
出版: (2003)

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.
由: Altfeld, M, et al.
出版: (2005)

Immediate dysfunction of vaccine-elicited CD8+ T cells primed in the absence of CD4+ T cells
由: Provine, N, et al.
出版: (2016)

Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection.
由: Yu, X, et al.
出版: (2002)

Polyvalent Gag-specific CD8 T-cells with enhanced functional properties are enriched in HIV-1 clade C infected individuals with lower viral loads
由: Julg, B, et al.
出版: (2009)

Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.
由: Thobakgale, C, et al.
出版: (2009)

The Glycopeptide PV-PS A1 Immunogen Elicits Both CD4+ and CD8+ Responses
由: Sharmeen Nishat, et al.
出版: (2024-12-01)

Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein.
由: Prado, J, et al.
出版: (2009)

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities.
由: Leitman, E, et al.
出版: (2017)

Dual CD47 and PD‐L1 blockade elicits anti‐tumor immunity by intratumoral CD8+ T cells
由: Susan N Christo, et al.
出版: (2024-01-01)

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality.
由: Mkhwanazi, N, et al.
出版: (2010)

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.
由: Martinez-Picado, J, et al.
出版: (2006)

Extensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections.
由: Rousseau, C, et al.
出版: (2007)

Rapid characterization of HIV clade C-specific cytotoxic T lymphocyte responses in infected African children and adults.
由: Goulder, P
出版: (2000)

S04-06 OA. Polyvalent Gag-specific CD8 T-cells with enhanced functional properties are enriched in HIV-1 clade C infected individuals with lower viral loads
由: Julg, B, et al.
出版: (2009)

Revisiting the Influence of HLA-type, Frequency, HLA-supertype and Homozygosity on the Immune Control of HIV
由: Leslie, A, et al.
出版: (2008)

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses
由: Stenler, S, et al.
出版: (2017)

Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains
由: Shixia Wang, et al.
出版: (2024-05-01)

Identification of a clade A HIV envelope immunogen from Protocol G that elicits neutralizing antibodies to tier 2 viruses
由: Hoffenberg S, et al.
出版: (2012-09-01)

CD39 Expression identifies terminally exhausted CD8+ T cells
由: Gupta, P, et al.
出版: (2015)

Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection.
由: Thobakgale, C, et al.
出版: (2011)