A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response.

In a significant proportion of melanoma patients, CTL specific for the melan-A(26/7-35) epitope can be detected in peripheral blood using HLA-A2/peptide tetramers. However, the functional capacity of these CTL has been controversial, since although they prove to be effective killers after in vitro e...

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Bibliographic Details
Main Authors:	Dunbar, P, Smith, C, Chao, D, Salio, M, Shepherd, D, Mirza, F, Lipp, M, Lanzavecchia, A, Sallusto, F, Evans, A, Russell-Jones, R, Harris, A, Cerundolo, V
Format:	Journal article
Language:	English
Published:	2000

A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response.

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