Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis.

The process by which fibronectin (FN), a soluble multidomain protein found in tissue fluids, forms insoluble fibrillar networks in the extracellular matrix is poorly understood. Cryptic sites found in FN type III domains have been hypothesized to function as nucleation points, thereby initiating fib...

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Bibliographic Details
Main Authors: Vakonakis, I, Staunton, D, Rooney, L, Campbell, I
Format: Journal article
Language:English
Published: 2007