Evidence for lack of cross-genotype protection of CD4+ T cell responses during chronic hepatitis C virus infection.

CD4+ T lymphocyte responses are thought to play a major role in control of the hepatitis C virus (HCV). Few, however, have been mapped down to the level of peptide and HLA restriction. Furthermore, the ability of such T cells to respond to viruses which differ in genotype has not been addressed in d...

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Bibliographic Details
Main Authors: Harcourt, G, Lucas, M, Godkin, A, Kantzanou, M, Phillips, R, Klenerman, P
Format: Journal article
Language:English
Published: 2003