Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

INTRODUCTION:Bile acids (BAs) are the end products of cholesterol metabolism produced by human and gut microbiome co-metabolism. Recent evidence suggests gut microbiota influence pathological features of Alzheimer's disease (AD) including neuroinflammation and amyloid-β deposition. METHOD:Serum...

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Main Authors: Nho, K, Kueider-Paisley, A, Mahmoudian-Dehkordi, S, Arnold, M, Risacher, SL, Louie, G, Blach, C, Baillie, R, Han, X, Kastenmüller, G, Jia, W, Xie, G, Ahmad, S, Hankemeier, T, van Duijn, CM, Trojanowski, JQ, Shaw, LM, Weiner, MW, Doraiswamy, PM, Saykin, AJ, Kaddurah-Daouk, R, Alzheimer'S Disease Neuroimaging Initiative And The Alzheimer Disease Metabolomics Consortium
Format: Journal article
Language:English
Published: Elsevier 2018

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