Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses

Antitumor immunity can be enhanced by the coordinated release and delivery of antigens and immune-stimulating agents to antigen-presenting cells via biodegradable vaccine carriers. So far, encapsulation of TLR ligands and tumor-associated antigens augmented cytotoxic T cell (CTLs) responses. Here, w...

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Bibliographic Details
Main Authors: Dölen, Y, Kreutz, M, Gileadi, U, Tel, J, Vasaturo, A, van Dinther, E, Hout-Kuijer, v, Cerundolo, V, Figdor, C
Format: Journal article
Language:English
Published: Taylor and Francis 2015