The Ba2+ block of the ATP-sensitive K+ current of mouse pancreatic beta-cells.

We studied the block of whole-cell ATP-sensitive K+ (KATP) currents in mouse pancreatic beta-cells produced by external Ba2+. Ba2+ produced a time-and voltage-dependent block of KATP currents, both the rate and extent of the block increasing with hyperpolarization. With 5.6 mM [K+]o, the relationshi...

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Những tác giả chính: Takano, M, Ashcroft, F
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1996