Activated T-follicular helper 2 cells are associated with disease activity in IgG4-related sclerosing cholangitis and pancreatitis

<p><strong>Objectives: </strong>Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) and autoimmune pancreatitis (AIP) are characterized by an abundance of circulating and tissue IgG4-positive plasma cells. T-follicular helper (Tfh) cells are necessary for B-cell differentiat...

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Bibliographic Details
Main Authors: Cargill, T, Makuch, M, Sadler, R, Lighaam, LC, Peters, R, Van Ham, M, Klenerman, P, Bateman, A, Rispens, T, Barnes, E, Culver, EL
Format: Journal article
Language:English
Published: Wolters Kluwer Health 2019