High-resolution analysis of cis-acting regulatory networks at the α-globin locus.
We have combined the circular chromosome conformation capture protocol with high-throughput, genome-wide sequence analysis to characterize the cis-acting regulatory network at a single locus. In contrast to methods which identify large interacting regions (10-1000 kb), the 4C approach provides a com...
Main Authors: | Hughes, J, Lower, K, Dunham, I, Taylor, S, De Gobbi, M, Sloane-Stanley, J, McGowan, S, Ragoussis, J, Vernimmen, D, Gibbons, R, Higgs, D |
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Format: | Journal article |
Language: | English |
Published: |
2013
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