Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

Lysosomal storage diseases (LSDs) often manifest with severe systemic and central nervous system (CNS) symptoms. The existing treatment options are limited and have no or only modest efficacy against neurological manifestations of disease. We demonstrate that recombinant human heat shock protein 70...

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Main Authors: Kirkegaard, T, Gray, J, Priestman, D, Wallom, K, Atkins, J, Olsen, O, Klein, A, Drndarski, S, Petersen, N, Ingemann, L, Smith, D, Morris, L, Bornæs, C, Jørgensen, S, Williams, I, Hinsby, A, Arenz, C, Begley, D, Jäättelä, M, Platt, F
格式: Journal article
语言:English
出版: American Association for the Advancement of Science 2016

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