Neisseria meningitidis native outer membrane vesicles containing different lipopolysaccharide glycoforms as adjuvants for meningococcal and nonmeningococcal antigens.

We evaluated the adjuvant effect of a modified glycoform of lipopolysaccharide (LPS) (LgtB-LpxL1) compared to that of the nonmodified glycoform Lpxl1 serogroup B meningococcal H44/76 native outer membrane vesicles (nOMVs) on immune responses to vaccination with the recombinant meningococcal protein,...

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Bibliographic Details
Main Authors: Nagaputra, J, Rollier, C, Sadarangani, M, Hoe, J, Mehta, O, Norheim, G, Saleem, M, Chan, H, Derrick, J, Feavers, I, Pollard, A, Moxon, E
Format: Journal article
Language:English
Published: 2014