Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

Persistent hepatitis C virus (HCV) infection is a major cause of chronic liver disease, worldwide. With the development of direct-acting antivirals, treatment of chronically infected patients has become highly effective, although a subset of patients responds less well to therapy. Sofosbuvir is a co...

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Detalhes bibliográficos
Main Authors: Smith, DA, Fernandez-Antunez, C, Magri, A, Bowden, R, Chaturvedi, N, Fellay, J, McLauchlan, J, Foster, GR, Irving, WL, Barnes, E, Simmonds, P, Pedergnana, V, Ramirez, S, Bukh, J, Ansari, MA
Outros Autores: STOP-HCV Consortium
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2021