Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.

We report synthesis of the first fluorescently labeled conjugates of risedronate (1), using an epoxide linker strategy enabling conjugation of 1 via its pyridyl nitrogen with the label (carboxyfluorescein). Unlike prior approaches to create fluorescent bisphosphonate probes, the new linking chemistr...

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Бібліографічні деталі
Автори: Kashemirov, B, Bala, J, Chen, X, Ebetino, F, Xia, Z, Russell, R, Coxon, F, Roelofs, A, Rogers, M, McKenna, C
Формат: Journal article
Мова:English
Опубліковано: 2008