Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.
We report synthesis of the first fluorescently labeled conjugates of risedronate (1), using an epoxide linker strategy enabling conjugation of 1 via its pyridyl nitrogen with the label (carboxyfluorescein). Unlike prior approaches to create fluorescent bisphosphonate probes, the new linking chemistr...
| Autors principals: | , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
2008
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