Recent developments in using mechanistic cardiac modelling for drug safety evaluation

On the tenth anniversary of two key International Conference on Harmonisation (ICH) guidelines relating to cardiac proarrhythmic safety, an initiative aims to consider the implementation of a new paradigm that combines in vitro and in silico technologies to improve risk assessment. The Comprehensive...

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Bibliographic Details
Main Authors: Mirams, G, Noble, D, Davies, M, Wang, K, Caruso, A, Walz, A, Lave, T, Schuler, F, Singer, T, Polonchuk, L
Format: Journal article
Published: Elsevier 2016