Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.

Numerous studies now support that human immunodeficiency virus type 1 (HIV-1) evolution is influenced by immune selection pressure, with population studies showing an association between specific HLA alleles and mutations within defined cytotoxic T-lymphocyte epitopes. Here we combine sequence data...

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Príomhchruthaitheoirí: Allen, T, Altfeld, M, Yu, X, O'Sullivan, K, Lichterfeld, M, Le Gall, S, John, M, Mothe, B, Lee, P, Kalife, E, Cohen, D, Freedberg, K, Strick, D, Johnston, M, Sette, A, Rosenberg, E, Mallal, SA, Goulder, P, Brander, C, Walker, B
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2004