Using chemical genetics and ATP analogues to dissect protein kinase function.
Protein kinases catalyze the transfer of the gamma-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurall...
Автори: | , , , |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2007
|