Using chemical genetics and ATP analogues to dissect protein kinase function.
Protein kinases catalyze the transfer of the gamma-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurall...
Päätekijät: | Elphick, L, Lee, SE, Gouverneur, V, Mann, D |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2007
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