Using chemical genetics and ATP analogues to dissect protein kinase function.

Using chemical genetics and ATP analogues to dissect protein kinase function.

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Protein kinases catalyze the transfer of the gamma-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurall...

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Dettagli Bibliografici
Autori principali:	Elphick, L, Lee, SE, Gouverneur, V, Mann, D
Natura:	Journal article
Lingua:	English
Pubblicazione:	2007

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