Using chemical genetics and ATP analogues to dissect protein kinase function.

Protein kinases catalyze the transfer of the gamma-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurall...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Elphick, L, Lee, SE, Gouverneur, V, Mann, D
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2007