Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a key signaling molecule in vascular homeostasis. Loss of NO bioavailability due to reduced synthesis and increased scavenging by reactive oxygen species is a cardinal feature of endothelial dysfunction in vascular disease s...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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