Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.

Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a key signaling molecule in vascular homeostasis. Loss of NO bioavailability due to reduced synthesis and increased scavenging by reactive oxygen species is a cardinal feature of endothelial dysfunction in vascular disease s...

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Autori principali: Alp, N, Channon, K
Natura: Journal article
Lingua:English
Pubblicazione: 2004