Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a key signaling molecule in vascular homeostasis. Loss of NO bioavailability due to reduced synthesis and increased scavenging by reactive oxygen species is a cardinal feature of endothelial dysfunction in vascular disease s...
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2004
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