Mutual information and variants for protein domain-domain contact prediction.

BACKGROUND: Predicting protein contacts solely based on sequence information remains a challenging problem, despite the huge amount of sequence data at our disposal. Mutual Information (MI), an information theory measure, has been extensively employed and modified to identify residues within a prot...

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Bibliographic Details
Main Authors: Gomes, M, Hamer, R, Reinert, G, Deane, C
Format: Journal article
Language:English
Published: BioMed Central 2012