Mutual information and variants for protein domain-domain contact prediction.
BACKGROUND: Predicting protein contacts solely based on sequence information remains a challenging problem, despite the huge amount of sequence data at our disposal. Mutual Information (MI), an information theory measure, has been extensively employed and modified to identify residues within a prot...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2012
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