JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis.
<p><strong>Objectives:</strong> The pathogenesis of osteoarthritis (OA) is poorly understood. Loss of the proteoglycan aggrecan from the cartilage is an early event. Recently, we identified a role for the JNK pathway, particularly JNK2, in human articular chondrocytes regulating ag...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2015
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