Conformational and thermodynamic properties of parallel intramolecular triple helices containing a DNA, RNA, or 2 '-OMeDNA third strand

The thermodynamic stability and solution conformational properties of three intramolecular triple helices based on the sequence AGAAGA-x-TCTTCT-x- TCTTCT (x is a non-nucleotide linker) comprising a DNA duplex and DNA, RNA, or 2'-OMeDNA third strands have been compared. The most stable triple he...

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Bibliographic Details
Main Authors: Asensio, J, Carr, R, Brown, T, Lane, A
Format: Journal article
Language:English
Published: 1999