Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine

Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine

Background One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. Methods We per...

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Bibliografiska uppgifter
Huvudupphovsmän:	Zongo, I, Somé, F, Somda, SA, Parikh, S, Rouamba, N, Rosenthal, P, Tarning, J, Lindegardh, N, Nosten, F, Ouédraogo, J
Materialtyp:	Journal article
Språk:	English
Publicerad:	Public Library of Science 2014

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