High DLL4 expression in tumour-associated vessels predicts for favorable radiotherapy outcome in locally advanced squamous cell head-neck cancer (HNSCC).

INTRODUCTION: Expression of the DLL4 (a notch pathway ligand) by tumor-associated endothelium is a postulated marker of vascular maturity and functionality. As vascular functionality is an important parameter defining chemotherapy and oxygen intra-tumoral distribution, we investigated the role of DL...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Koukourakis, M, Giatromanolaki, A, Sivridis, E, Gatter, K, Harris, A
Formaat: Journal article
Taal:English
Gepubliceerd in: 2013