Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice.

CD4+ T cells in the mouse can be subdivided into two fractions based on the level of expression of the CD45RB determinant. Previous studies have shown that these subsets are functionally distinct. We have further characterized the properties of these subpopulations in vivo by injecting them into C....

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Bibliographic Details
Main Authors: Powrie, F, Leach, M, Mauze, S, Caddle, L, Coffman, R
Format: Journal article
Language:English
Published: 1993