Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice.
CD4+ T cells in the mouse can be subdivided into two fractions based on the level of expression of the CD45RB determinant. Previous studies have shown that these subsets are functionally distinct. We have further characterized the properties of these subpopulations in vivo by injecting them into C....
Main Authors: | Powrie, F, Leach, M, Mauze, S, Caddle, L, Coffman, R |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
1993
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פריטים דומים
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Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.
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Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.
מאת: Powrie, F, et al.
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An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
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יצא לאור: (1999) -
CD45RBHIGH CD4+ T-CELLS INDUCE A PATHOGENIC TH1 RESPONSE IN THE COLON WHEN TRANSFERRED TO C-B-17 SCID MICE WHICH IS PREVENTED BY CO-TRANSFER OF THE CD45RBLOW POPULATION
מאת: Powrie, F, et al.
יצא לאור: (1994) -
CD4+ T-cells in the regulation of inflammatory responses in the intestine.
מאת: Powrie, F, et al.
יצא לאור: (1997)