Stochastic modelling and simulation in cell biology

Stochastic modelling and simulation in cell biology

<p>Modelling and simulation are essential to modern research in cell biology. This thesis follows a journey starting from the construction of new stochastic methods for discrete biochemical systems to using them to simulate a population of interacting haematopoietic stem cell lineages.</p&g...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Szekely, T, Tamas Szekely
Awduron Eraill:	Burrage, K
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2014
Pynciau:	Probability theory and stochastic processes Biology and other natural sciences (mathematics) Computational biochemistry Biology (medical sciences) Cell Biology (see also Plant sciences) Chemical kinetics Biology Computer science (mathematics) Mathematical biology Stem cells (clinical sciences)

Eitemau Tebyg

Structure-function studies of fibronectin domains in the human endometrium
gan: Mok, M, et al.
Cyhoeddwyd: (2008)

Computational biology and the limits of shared vision
gan: Carusi, A
Cyhoeddwyd: (2009)

The role and regulation of Asterless in the centrosome cycle
gan: Novak, ZA
Cyhoeddwyd: (2014)

Towards understanding the mechanism of cohesin loading
gan: Dixon, SE
Cyhoeddwyd: (2013)

Functions of conserved centriole proteins in African trypanosomes
gan: Scheumann, N
Cyhoeddwyd: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
gan: Kesoglidou, PX
Cyhoeddwyd: (2012)

Forum for scientific method in biology: transcript
gan: Carusi, A, et al.
Cyhoeddwyd: (2009)

Aspects to T-cell phenotype during infection with HIV, CMV and Hepatitis C virus
gan: Northfield, J
Cyhoeddwyd: (2008)

The role of protein kinase C in platelet activation
gan: Unsworth, AJ
Cyhoeddwyd: (2012)

Vertex model approaches to epithelial tissues in developmental systems
gan: Smith, A
Cyhoeddwyd: (2012)

Regulation of E2F-1 by methylation and NEDDylation
gan: Loftus, S, et al.
Cyhoeddwyd: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
gan: Grijzenhout, A
Cyhoeddwyd: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
gan: Schulz, J
Cyhoeddwyd: (2013)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
gan: Peterneva, K
Cyhoeddwyd: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
gan: Halstead, J
Cyhoeddwyd: (2013)

Mathematical models of cranial neural crest cell migration
gan: Dyson, L
Cyhoeddwyd: (2013)

Pathways for glycoprotein degradation in mammalian cells
gan: Kukushkin, N, et al.
Cyhoeddwyd: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
gan: Gibson, K
Cyhoeddwyd: (2011)

Functional analysis of cancer/testis antigens in human cancer
gan: Pagotto, A
Cyhoeddwyd: (2013)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
gan: Feldinger, K
Cyhoeddwyd: (2012)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
gan: Moss, J
Cyhoeddwyd: (2011)

Cell stress response and hypoxia in breast cancer
gan: Milani, M, et al.
Cyhoeddwyd: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
gan: Johnson, J
Cyhoeddwyd: (2011)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
gan: Phipps, L
Cyhoeddwyd: (2011)

Effective design of marine reserves: incorporating alongshore currents, size structure, and uncertainty
gan: Reimer, J
Cyhoeddwyd: (2013)

Stochastic modelling of the cell cycle
gan: He, E
Cyhoeddwyd: (2012)

Recent modelling frameworks for systems of interacting particles
gan: Franz, B
Cyhoeddwyd: (2014)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
gan: Duncan, T
Cyhoeddwyd: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
gan: Khan, FF
Cyhoeddwyd: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
gan: Portman, N
Cyhoeddwyd: (2011)

Tet2 and relevant potential intervention in cancer
gan: Zauri, M
Cyhoeddwyd: (2014)

Induced regulatory T cells in transplantation tolerance
gan: Chen, Y
Cyhoeddwyd: (2010)

Towards a computational model of the colonic crypt with a realistic, deformable geometry
gan: Dunn, S
Cyhoeddwyd: (2011)

Cell fate mechanisms in colorectal cancer
gan: Kay, SK
Cyhoeddwyd: (2014)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
gan: Ledaki, I
Cyhoeddwyd: (2013)

The evolution of eukaryotic cilia
gan: Hodges, M, et al.
Cyhoeddwyd: (2011)

Confocal single-molecule fluorescence as a tool for investigating biomolecular dynamics in vitro and in vivo
gan: Torella, J, et al.
Cyhoeddwyd: (2011)

The mechanism of Nov (CCN3) function in haematopoiesis
gan: Guo, Y
Cyhoeddwyd: (2012)

Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
gan: Bakshi, S
Cyhoeddwyd: (2013)

Mechanisms of induction and modulation of the pro-inflammatory cytokine interleukin-1beta
gan: Yip, RHN
Cyhoeddwyd: (2012)