Stochastic modelling and simulation in cell biology

Stochastic modelling and simulation in cell biology

<p>Modelling and simulation are essential to modern research in cell biology. This thesis follows a journey starting from the construction of new stochastic methods for discrete biochemical systems to using them to simulate a population of interacting haematopoietic stem cell lineages.</p&g...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Szekely, T, Tamas Szekely
Rannpháirtithe:	Burrage, K
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2014
Ábhair:	Probability theory and stochastic processes Biology and other natural sciences (mathematics) Computational biochemistry Biology (medical sciences) Cell Biology (see also Plant sciences) Chemical kinetics Biology Computer science (mathematics) Mathematical biology Stem cells (clinical sciences)

Míreanna comhchosúla

Structure-function studies of fibronectin domains in the human endometrium
de réir: Mok, M, et al.
Foilsithe / Cruthaithe: (2008)

Computational biology and the limits of shared vision
de réir: Carusi, A
Foilsithe / Cruthaithe: (2009)

The role and regulation of Asterless in the centrosome cycle
de réir: Novak, ZA
Foilsithe / Cruthaithe: (2014)

Towards understanding the mechanism of cohesin loading
de réir: Dixon, SE
Foilsithe / Cruthaithe: (2013)

Functions of conserved centriole proteins in African trypanosomes
de réir: Scheumann, N
Foilsithe / Cruthaithe: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
de réir: Kesoglidou, PX
Foilsithe / Cruthaithe: (2012)

Forum for scientific method in biology: transcript
de réir: Carusi, A, et al.
Foilsithe / Cruthaithe: (2009)

Aspects to T-cell phenotype during infection with HIV, CMV and Hepatitis C virus
de réir: Northfield, J
Foilsithe / Cruthaithe: (2008)

The role of protein kinase C in platelet activation
de réir: Unsworth, AJ
Foilsithe / Cruthaithe: (2012)

Vertex model approaches to epithelial tissues in developmental systems
de réir: Smith, A
Foilsithe / Cruthaithe: (2012)

Regulation of E2F-1 by methylation and NEDDylation
de réir: Loftus, S, et al.
Foilsithe / Cruthaithe: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
de réir: Grijzenhout, A
Foilsithe / Cruthaithe: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
de réir: Schulz, J
Foilsithe / Cruthaithe: (2013)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
de réir: Peterneva, K
Foilsithe / Cruthaithe: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
de réir: Halstead, J
Foilsithe / Cruthaithe: (2013)

Mathematical models of cranial neural crest cell migration
de réir: Dyson, L
Foilsithe / Cruthaithe: (2013)

Pathways for glycoprotein degradation in mammalian cells
de réir: Kukushkin, N, et al.
Foilsithe / Cruthaithe: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
de réir: Gibson, K
Foilsithe / Cruthaithe: (2011)

Functional analysis of cancer/testis antigens in human cancer
de réir: Pagotto, A
Foilsithe / Cruthaithe: (2013)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
de réir: Feldinger, K
Foilsithe / Cruthaithe: (2012)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
de réir: Moss, J
Foilsithe / Cruthaithe: (2011)

Cell stress response and hypoxia in breast cancer
de réir: Milani, M, et al.
Foilsithe / Cruthaithe: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
de réir: Johnson, J
Foilsithe / Cruthaithe: (2011)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
de réir: Phipps, L
Foilsithe / Cruthaithe: (2011)

Effective design of marine reserves: incorporating alongshore currents, size structure, and uncertainty
de réir: Reimer, J
Foilsithe / Cruthaithe: (2013)

Stochastic modelling of the cell cycle
de réir: He, E
Foilsithe / Cruthaithe: (2012)

Recent modelling frameworks for systems of interacting particles
de réir: Franz, B
Foilsithe / Cruthaithe: (2014)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
de réir: Duncan, T
Foilsithe / Cruthaithe: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
de réir: Khan, FF
Foilsithe / Cruthaithe: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
de réir: Portman, N
Foilsithe / Cruthaithe: (2011)

Tet2 and relevant potential intervention in cancer
de réir: Zauri, M
Foilsithe / Cruthaithe: (2014)

Induced regulatory T cells in transplantation tolerance
de réir: Chen, Y
Foilsithe / Cruthaithe: (2010)

Towards a computational model of the colonic crypt with a realistic, deformable geometry
de réir: Dunn, S
Foilsithe / Cruthaithe: (2011)

Cell fate mechanisms in colorectal cancer
de réir: Kay, SK
Foilsithe / Cruthaithe: (2014)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
de réir: Ledaki, I
Foilsithe / Cruthaithe: (2013)

The evolution of eukaryotic cilia
de réir: Hodges, M, et al.
Foilsithe / Cruthaithe: (2011)

Confocal single-molecule fluorescence as a tool for investigating biomolecular dynamics in vitro and in vivo
de réir: Torella, J, et al.
Foilsithe / Cruthaithe: (2011)

The mechanism of Nov (CCN3) function in haematopoiesis
de réir: Guo, Y
Foilsithe / Cruthaithe: (2012)

Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
de réir: Bakshi, S
Foilsithe / Cruthaithe: (2013)

Mechanisms of induction and modulation of the pro-inflammatory cytokine interleukin-1beta
de réir: Yip, RHN
Foilsithe / Cruthaithe: (2012)