Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles.

BACKGROUND: Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis (RA), and associate with HLA-DRB1 shared epitope (SE) alleles. OBJECTIVE: To investigate reactivities of anti-CCP to various citrullinated proteins/peptides, which represent...

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Bibliographic Details
Main Authors: Snir, O, Widhe, M, von Spee, C, Lindberg, J, Padyukov, L, Lundberg, K, Engström, A, Venables, P, Lundeberg, J, Holmdahl, R, Klareskog, L, Malmström, V
Format: Journal article
Language:English
Published: 2009