Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border.

BACKGROUND: Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug...

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Bibliographic Details
Main Authors: Takeuchi, R, Lawpoolsri, S, Imwong, M, Kobayashi, J, Kaewkungwal, J, Pukrittayakamee, S, Puangsa-art, S, Thanyavanich, N, Maneeboonyang, W, Day, N, Singhasivanon, P
Format: Journal article
Language:English
Published: BioMed Central 2010