Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Nešić, D, Buti, L, Lu, X, Stebbins, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2014

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