Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...

Descripció completa

Dades bibliogràfiques
Autors principals: Nešić, D, Buti, L, Lu, X, Stebbins, C
Format: Journal article
Idioma:English
Publicat: 2014