Targeting ALK2: an open science approach to developing therapeutics for the treatment of diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma is an aggressive pediatric cancer for which no effective chemotherapeutic drugs exist. Analysis of the genomic landscape of this disease has led to the identification of the serine/threonine kinase ALK2 as a potential target for therapeutic intervention. In this work...

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Bibliographic Details
Main Authors: Ensan, D, Smil, D, Zepeda-Velázquez, CA, Panagopoulos, D, Wong, JF, Williams, EP, Adamson, R, Bullock, AN, Kiyota, T, Aman, A, Roberts, OG, Edwards, AM, O'Meara, JA, Isaac, MB, Al-Awar, R
Format: Journal article
Language:English
Published: American Chemical Society 2020