Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

CONTEXT: Variation in the region of chromosome 8 including the genes steroid 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism. However, the relative importance of polymorphisms in CYP11B1 and CYP11B2 in determining these pheno...

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Bibliographic Details
Main Authors: Imrie, H, Freel, M, Mayosi, B, Davies, E, Fraser, R, Ingram, M, Cordell, H, Farrall, M, Avery, P, Watkins, H, Keavney, B, Connell, J
Format: Journal article
Language:English
Published: 2006