An axonal brake on striatal dopamine output by cholinergic interneurons

An axonal brake on striatal dopamine output by cholinergic interneurons

Depolarization of axons is necessary for somatic action potentials to trigger axonal neurotransmitter release. We show that striatal cholinergic interneurons (ChIs) and nicotinic receptors (nAChRs) on mouse dopamine axons interrupt this relationship. Following nAChRmediated depolarization, dopamine...

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Dettagli Bibliografici
Autori principali:	Zhang, Y-F, Luan, P, Qiao, Q, He, Y, Zatka-Haas, P, Zhang, G, Lin, MZ, Lak, A, Jing, M, Mann, EO, Cragg, SJ
Natura:	Journal article
Lingua:	English
Pubblicazione:	Springer Nature 2025

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