MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

MYH associated polyposis is a hereditary syndrome responsible for early colorectal cancer with a distinct genetic pathway from the Familial Adenomatous Polyposis or the Hereditary Non Polyposis Colorectal Cancer syndrome. We have studied a family with three members bearing a biallelic mutation in MY...

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Bibliographic Details
Main Authors:	Lefevre, J, Colas, C, Coulet, F, Bonilla, C, Mourra, N, Flejou, J, Tiret, E, Bodmer, W, Soubrier, F, Parc, Y
Format:	Journal article
Language:	English
Published:	2010

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