Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine
The leading malaria vaccine in development is the circumsporozoite (CS) protein-based vaccine, RTS,S, which targets the pre-erythrocytic stage of Plasmodium falciparum infection. It induces modest levels of protective efficacy largely mediated by CS specific antibodies. We aimed to enhance vaccine e...
| Main Authors: | , , , , |
|---|---|
| 格式: | Journal article |
| 出版: |
Nature Publishing Group
2017
|