Identification of contact residues in the IgE binding site of human FcεRIα
The high-affinity receptor for immunoglobulin E (IgE), FcεRI, is an αβγ2 tetramer found on mast cells, basophils, and several other types of immune effector cells. The interaction of IgE with the α-subunit of FcεRI is central to the pathogenesis of allergy. Detailed knowledge of the mode of interact...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1997
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