Identification of contact residues in the IgE binding site of human FcεRIα

The high-affinity receptor for immunoglobulin E (IgE), FcεRI, is an αβγ2 tetramer found on mast cells, basophils, and several other types of immune effector cells. The interaction of IgE with the α-subunit of FcεRI is central to the pathogenesis of allergy. Detailed knowledge of the mode of interact...

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Detaylı Bibliyografya
Asıl Yazarlar: Cook, J, Henry, A, McDonnell, J, Owens, R, Sutton, B, Gould, H
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 1997