Mutational signature distribution varies with DNA replication timing and strand asymmetry
<strong>Background:</strong> DNA replication plays an important role in mutagenesis, yet little is known about how it interacts with other mutagenic processes. Here, we use somatic mutation signatures – each representing a mutagenic process – derived from 3056 patients spanning 19 cancer...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
BioMed Central
2018
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