Mutational signature distribution varies with DNA replication timing and strand asymmetry

Mutational signature distribution varies with DNA replication timing and strand asymmetry

<strong>Background:</strong> DNA replication plays an important role in mutagenesis, yet little is known about how it interacts with other mutagenic processes. Here, we use somatic mutation signatures – each representing a mutagenic process – derived from 3056 patients spanning 19 cancer...

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Bibliographic Details
Main Authors:	Tomkova, M, Tomek, J, Kriaucionis, S, Schuster-Boeckler, PB
Format:	Journal article
Published:	BioMed Central 2018

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