Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) study.

BACKGROUND: Ischemic stroke is the leading cause of mortality worldwide and a major contributor to neurological disability and dementia. Terutroban is a specific TP receptor antagonist with antithrombotic, antivasoconstrictive, and antiatherosclerotic properties, which may be of interest for the se...

Full description

Bibliographic Details
Main Authors: Bousser, MG, Amarenco, P, Chamorro, A, Fisher, M, Ford, I, Fox, K, Hennerici, MG, Mattle, H, Rothwell, P
Format: Journal article
Language:English
Published: 2009